Recognition of 5-methyl-CG and CG base pairs in duplex DNA with high stability using antiparallel-type triplex-forming oligonucleotides with 2-guanidinoethyl-2′-deoxynebularine

The formation of triplex DNA is a site-specific recognition method that directly targets duplex DNA. However, triplex DNA formation is generally formed for the GC and AT base pairs of duplex DNA, and there are no natural nucleotides that recognize the CG and TA base pairs, or even the 5-methyl-CG ((...

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Detalles Bibliográficos
Autores principales: Notomi, Ryotaro, Sasaki, Shigeki, Taniguchi, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757063/
https://www.ncbi.nlm.nih.gov/pubmed/36454012
http://dx.doi.org/10.1093/nar/gkac1110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757063/
https://www.ncbi.nlm.nih.gov/pubmed/36454012
http://dx.doi.org/10.1093/nar/gkac1110

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