DDX17 helicase promotes resolution of R-loop-mediated transcription–replication conflicts in human cells

R-loops are three-stranded nucleic acid structures composed of an RNA:DNA hybrid and displaced DNA strand. These structures can halt DNA replication when formed co-transcriptionally in the opposite orientation to replication fork progression. A recent study has shown that replication forks stalled b...

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Detalles Bibliográficos
Autores principales: Boleslavska, Barbora, Oravetzova, Anna, Shukla, Kaustubh, Nascakova, Zuzana, Ibini, Oluwakemi Ngozi, Hasanova, Zdenka, Andrs, Martin, Kanagaraj, Radhakrishnan, Dobrovolna, Jana, Janscak, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757067/
https://www.ncbi.nlm.nih.gov/pubmed/36453994
http://dx.doi.org/10.1093/nar/gkac1116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757067/
https://www.ncbi.nlm.nih.gov/pubmed/36453994
http://dx.doi.org/10.1093/nar/gkac1116

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