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Density-based detection of cell transition states to construct disparate and bifurcating trajectories

Tree- and linear-shaped cell differentiation trajectories have been widely observed in developmental biologies and can be also inferred through computational methods from single-cell RNA-sequencing datasets. However, trajectories with complicated topologies such as loops, disparate lineages and bifu...

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Detalles Bibliográficos
Autores principales: Lan, Tian, Hutvagner, Gyorgy, Zhang, Xuan, Liu, Tao, Wong, Limsoon, Li, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757071/
https://www.ncbi.nlm.nih.gov/pubmed/36124665
http://dx.doi.org/10.1093/nar/gkac785