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scAB detects multiresolution cell states with clinical significance by integrating single-cell genomics and bulk sequencing data

Although single-cell sequencing has provided a powerful tool to deconvolute cellular heterogeneity of diseases like cancer, extrapolating clinical significance or identifying clinically-relevant cells remains challenging. Here, we propose a novel computational method scAB, which integrates single-ce...

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Detalles Bibliográficos
Autores principales: Zhang, Qinran, Jin, Suoqin, Zou, Xiufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757078/
https://www.ncbi.nlm.nih.gov/pubmed/36440766
http://dx.doi.org/10.1093/nar/gkac1109