Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element

T helper 17 (Th17) cells regulate mucosal barrier defenses, but also promote multiple autoinflammatory diseases. Although many molecular determinants of Th17 cell differentiation have been elucidated, the transcriptional programs that sustain Th17 cells in vivo remain obscure. The transcription fact...

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Detalles Bibliográficos
Autores principales: Hall, Jason A., Pokrovskii, Maria, Kroehling, Lina, Kim, Bo-Ram, Kim, Seung Yong, Wu, Lin, Lee, June-Yong, Littman, Dan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757081/
https://www.ncbi.nlm.nih.gov/pubmed/36243007
http://dx.doi.org/10.1016/j.immuni.2022.09.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757081/
https://www.ncbi.nlm.nih.gov/pubmed/36243007
http://dx.doi.org/10.1016/j.immuni.2022.09.013

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