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Suppression of prostate cancer and amelioration of the immunosuppressive tumor microenvironment through selective immunoproteasome inhibition

New treatment options to battle hormone-refractory prostate carcinoma (PC) are a pressing medical need. Chronic inflammation has been implicated in PC etiology. The pro-inflammatory cytokines IL-6, IL-23 and IL-17 are key mediators to promote growth of PC. Here, we evaluate the potential of immunopr...

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Detalles Bibliográficos
Autores principales: Koerner, Julia, Horvath, Dennis, Oliveri, Franziska, Li, Jun, Basler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757486/
https://www.ncbi.nlm.nih.gov/pubmed/36531689
http://dx.doi.org/10.1080/2162402X.2022.2156091