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Exploring the genetic architecture of protein secretion in Komagataella phaffii (Pichia pastoris) for biotechnology applications

Improvements to the production of proteins in industrial yeast species have largely relied on generating variation in a single genetic background. A new study in PLOS Biology leverages natural genetic variation to identify genes and variants with the potential to improve protein yield.

Detalles Bibliográficos
Autores principales: Swichkow, Chantle Reiko, Bloom, Joshua S., Kruglyak, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757564/
https://www.ncbi.nlm.nih.gov/pubmed/36525401
http://dx.doi.org/10.1371/journal.pbio.3001911