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Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response

CISD-1/mitoNEET is an evolutionarily conserved outer mitochondrial membrane [2Fe-2S] protein that regulates mitochondrial function and morphology. The [2Fe-2S] clusters are redox reactive and shown to mediate oxidative stress in vitro and in vivo. However, there is limited research studying CISD-1/m...

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Detalles Bibliográficos
Autores principales: Boos, Jacob R., Jandrain, Hanna N., Hagiuda, Emi, Taguchi, Alexander T., Hasegawa, Kazuya, Fedun, Bailey L., Taylor, Sarah J., Elad, Sofhia M., Faber, Sarah E., Kumasaka, Takashi, Iwasaki, Toshio, Geldenhuys, Werner J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757825/
https://www.ncbi.nlm.nih.gov/pubmed/36533211
http://dx.doi.org/10.1016/j.arres.2022.100048