Cargando…
Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies
Tumour heterogeneity is thought to be a major barrier to successful cancer treatment due to the presence of drug resistant clonal lineages. However, identifying the characteristics of such lineages that underpin resistance to therapy has remained challenging. Here, we utilise clonal transcriptomics...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757829/ https://www.ncbi.nlm.nih.gov/pubmed/36525288 http://dx.doi.org/10.7554/eLife.80981 |