Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice

Microglia are critical regulators of brain development that engulf synaptic proteins during postnatal synapse remodeling. However, the mechanisms through which microglia sense the brain environment are not well defined. Here, we characterized the regulatory program downstream of interleukin-33 (IL-3...

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Detalles Bibliográficos
Autores principales: Han, Rafael T., Vainchtein, Ilia D., Schlachetzki, Johannes C.M., Cho, Frances S., Dorman, Leah C., Ahn, Eunji, Kim, Dong Kyu, Barron, Jerika J., Nakao-Inoue, Hiromi, Molofsky, Ari B., Glass, Christopher K., Paz, Jeanne T., Molofsky, Anna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757845/
https://www.ncbi.nlm.nih.gov/pubmed/36520518
http://dx.doi.org/10.1084/jem.20220605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757845/
https://www.ncbi.nlm.nih.gov/pubmed/36520518
http://dx.doi.org/10.1084/jem.20220605

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