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Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice
Microglia are critical regulators of brain development that engulf synaptic proteins during postnatal synapse remodeling. However, the mechanisms through which microglia sense the brain environment are not well defined. Here, we characterized the regulatory program downstream of interleukin-33 (IL-3...
Autores principales: | Han, Rafael T., Vainchtein, Ilia D., Schlachetzki, Johannes C.M., Cho, Frances S., Dorman, Leah C., Ahn, Eunji, Kim, Dong Kyu, Barron, Jerika J., Nakao-Inoue, Hiromi, Molofsky, Ari B., Glass, Christopher K., Paz, Jeanne T., Molofsky, Anna V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757845/ https://www.ncbi.nlm.nih.gov/pubmed/36520518 http://dx.doi.org/10.1084/jem.20220605 |
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