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The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis

α-Catenin couples the cadherin–catenin complex to the actin cytoskeleton. The mechanosensitive α-Catenin M region undergoes conformational changes upon application of force to recruit interaction partners. Here, we took advantage of the tension landscape in the Drosophila embryo to define three diff...

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Detalles Bibliográficos
Autores principales: Sheppard, Luka, Green, David G., Lerchbaumer, Gerald, Rothenberg, Katheryn E., Fernandez-Gonzalez, Rodrigo, Tepass, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757846/
https://www.ncbi.nlm.nih.gov/pubmed/36520419
http://dx.doi.org/10.1083/jcb.202108091