Polarity of the CRISPR roadblock to transcription

CRISPR (clustered regularly interspaced short palindromic repeats) utility relies on a stable Cas effector complex binding to its target site. However, a Cas complex bound to DNA may be removed by motor proteins carrying out host processes and the mechanism governing this removal remains unclear. In...

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Detalles Bibliográficos
Autores principales: Hall, Porter M., Inman, James T., Fulbright, Robert M., Le, Tung T., Brewer, Joshua J., Lambert, Guillaume, Darst, Seth A., Wang, Michelle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758054/
https://www.ncbi.nlm.nih.gov/pubmed/36471058
http://dx.doi.org/10.1038/s41594-022-00864-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758054/
https://www.ncbi.nlm.nih.gov/pubmed/36471058
http://dx.doi.org/10.1038/s41594-022-00864-x

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