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Polarity of the CRISPR roadblock to transcription
CRISPR (clustered regularly interspaced short palindromic repeats) utility relies on a stable Cas effector complex binding to its target site. However, a Cas complex bound to DNA may be removed by motor proteins carrying out host processes and the mechanism governing this removal remains unclear. In...
Autores principales: | Hall, Porter M., Inman, James T., Fulbright, Robert M., Le, Tung T., Brewer, Joshua J., Lambert, Guillaume, Darst, Seth A., Wang, Michelle D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758054/ https://www.ncbi.nlm.nih.gov/pubmed/36471058 http://dx.doi.org/10.1038/s41594-022-00864-x |
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