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Histone Deacetylase 3 Inhibition Decreases Cerebral Edema and Protects the Blood–Brain Barrier After Stroke

We have previously shown that selective inhibition of histone deacetylase 3 (HDAC3) decreases infarct volume and improves long-term functional outcomes after stroke. In this study, we examined the effects of HDAC3 inhibition on cerebral edema and blood–brain barrier (BBB) leakage and explored its un...

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Detalles Bibliográficos
Autores principales: Lu, Hui, Ashiqueali, Ryan, Lin, Chin I, Walchale, Aashlesha, Clendaniel, Victoria, Matheson, Rudy, Fisher, Marc, Lo, Eng H., Selim, Magdy, Shehadah, Amjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758108/
https://www.ncbi.nlm.nih.gov/pubmed/36258136
http://dx.doi.org/10.1007/s12035-022-03083-z