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Hepatic neddylation deficiency triggers fatal liver injury via inducing NF-κB-inducing kinase in mice

The conjugation of neural precursor cell expressed, developmentally downregulated 8 (NEDD8) to target proteins, termed neddylation, participates in many cellular processes and is aberrant in various pathological diseases. Its relevance to liver function and failure remains poorly understood. Herein,...

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Detalles Bibliográficos
Autores principales: Xu, Cheng, Zhou, Hongyi, Jin, Yulan, Sahay, Khushboo, Robicsek, Anna, Liu, Yisong, Dong, Kunzhe, Zhou, Jiliang, Barrett, Amanda, Su, Huabo, Chen, Weiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758150/
https://www.ncbi.nlm.nih.gov/pubmed/36526632
http://dx.doi.org/10.1038/s41467-022-35525-6