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Hepatic neddylation deficiency triggers fatal liver injury via inducing NF-κB-inducing kinase in mice
The conjugation of neural precursor cell expressed, developmentally downregulated 8 (NEDD8) to target proteins, termed neddylation, participates in many cellular processes and is aberrant in various pathological diseases. Its relevance to liver function and failure remains poorly understood. Herein,...
Autores principales: | Xu, Cheng, Zhou, Hongyi, Jin, Yulan, Sahay, Khushboo, Robicsek, Anna, Liu, Yisong, Dong, Kunzhe, Zhou, Jiliang, Barrett, Amanda, Su, Huabo, Chen, Weiqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758150/ https://www.ncbi.nlm.nih.gov/pubmed/36526632 http://dx.doi.org/10.1038/s41467-022-35525-6 |
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