Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice

Dysregulation of mTOR complex 1 (mTORC1) activity drives neuromuscular junction (NMJ) structural instability during aging; however, downstream targets mediating this effect have not been elucidated. Here, we investigate the roles of two mTORC1 phosphorylation targets for mRNA translation, ribosome p...

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Detalles Bibliográficos
Autores principales: Ang, Seok-Ting J., Crombie, Elisa M., Dong, Han, Tan, Kuan-Ting, Hernando, Adriel, Yu, Dejie, Adamson, Stuart, Kim, Seonyoung, Withers, Dominic J., Huang, Hua, Tsai, Shih-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758177/
https://www.ncbi.nlm.nih.gov/pubmed/36526657
http://dx.doi.org/10.1038/s41467-022-35547-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758177/
https://www.ncbi.nlm.nih.gov/pubmed/36526657
http://dx.doi.org/10.1038/s41467-022-35547-0

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