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Low aerobic capacity in McArdle disease: A role for mitochondrial network impairment?
BACKGROUND: McArdle disease is caused by myophosphorylase deficiency and results in complete inability for muscle glycogen breakdown. A hallmark of this condition is muscle oxidation impairment (e.g., low peak oxygen uptake (VO(2peak))), a phenomenon traditionally attributed to reduced glycolytic fl...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758572/ https://www.ncbi.nlm.nih.gov/pubmed/36455789 http://dx.doi.org/10.1016/j.molmet.2022.101648 |