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Effect of EGFR amplification on the prognosis of EGFR-mutated advanced non–small-cell lung cancer patients: a prospective observational study

BACKGROUND: Epidermal growth factor receptor (EGFR) amplification refers to the copy number increase of EGFR gene, and is often identified as a “bypass” way of Epidermal growth factor receptor Tyrosine kinase inhibitors (EGFR-TKI) resistance. We aimed to explore the effect of EGFR amplification on E...

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Detalles Bibliográficos
Autores principales: Peng, Duanyang, Liang, Pingan, Zhong, Congying, Xu, Peng, He, Yanqing, Luo, Yuxi, Wang, Xia, Liu, Anwen, Zeng, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758842/
https://www.ncbi.nlm.nih.gov/pubmed/36528578
http://dx.doi.org/10.1186/s12885-022-10390-0