Safety and efficacy of RT234 vardenafil inhalation powder on exercise parameters in pulmonary arterial hypertension: phase II, dose-escalation study design

BACKGROUND: Pulmonary arterial hypertension (PAH) is a progressive disease characterized by high mean pulmonary arterial pressure (≥ 20 mmHg) and remodeling of the vascular arteries. Approved therapies improve symptoms and delay clinical worsening in the long term, but they do not relieve acute exer...

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Detalles Bibliográficos
Autores principales: Benza, Raymond L., Franco, Veronica, Aras, Mandar A., Spikes, Leslie, Grinnan, Daniel, Satler, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758858/
https://www.ncbi.nlm.nih.gov/pubmed/36527025
http://dx.doi.org/10.1186/s12931-022-02262-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758858/
https://www.ncbi.nlm.nih.gov/pubmed/36527025
http://dx.doi.org/10.1186/s12931-022-02262-9

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