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Defibrotide improved the outcome of monocrotaline induced rat hepatic sinusoidal obstruction syndrome

BACKGROUND AND AIM: Pyrrolizidine alkaloids (PA) induced hepatic sinusoidal obstruction syndrome (HSOS) occurred worldwide and the mortality rate remained high because there were no specific therapies. Defibrotide was effective for HSOS following hematopoietic stem cell transplantation. But the path...

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Detalles Bibliográficos
Autores principales: Liu, Zhenli, Liang, Shan, Wei, Xinhuan, Du, Xiaofei, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758875/
https://www.ncbi.nlm.nih.gov/pubmed/36526956
http://dx.doi.org/10.1186/s12876-022-02523-3