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How do we know a treatment is good enough? A survey of non-inferiority trials

BACKGROUND: Non-inferiority and equivalence trials aim to determine whether a new treatment is good enough (non-inferior) or as good as (equivalent to) another treatment. To inform the decision about non-inferiority or equivalence, a margin is used. We aimed to identify the current methods used to d...

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Detalles Bibliográficos
Autores principales: Attard, Naomi, Totton, Nikki, Gillies, Katie, Goulao, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758907/
https://www.ncbi.nlm.nih.gov/pubmed/36527129
http://dx.doi.org/10.1186/s13063-022-06911-8