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Multivalent viral particles elicit safe and efficient immunoprotection against Nipah Hendra and Ebola viruses

Experimental vaccines for the deadly zoonotic Nipah (NiV), Hendra (HeV), and Ebola (EBOV) viruses have focused on targeting individual viruses, although their geographical and bat reservoir host overlaps warrant creation of multivalent vaccines. Here we explored whether replication-incompetent pseud...

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Detalles Bibliográficos
Autores principales: Ithinji, Duncan G., Buchholz, David W., Ezzatpour, Shahrzad, Monreal, I. Abrrey, Cong, Yu, Sahler, Julie, Bangar, Amandip Singh, Imbiakha, Brian, Upadhye, Viraj, Liang, Janie, Ma, Andrew, Bradel-Tretheway, Birgit, Kaza, Benjamin, Yeo, Yao Yu, Choi, Eun Jin, Johnston, Gunner P., Huzella, Louis, Kollins, Erin, Dixit, Saurabh, Yu, Shuiqing, Postnikova, Elena, Ortega, Victoria, August, Avery, Holbrook, Michael R., Aguilar, Hector C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759047/
https://www.ncbi.nlm.nih.gov/pubmed/36528644
http://dx.doi.org/10.1038/s41541-022-00588-5