ACE2 and TMPRSS2 SARS-CoV-2 infectivity genes: deep mutational scanning and characterization of missense variants

The human angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) proteins play key roles in the cellular internalization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the coronavirus responsible for the coronavirus disease of 2019 (COVID-19) pandemic....

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Lingxin, Sarangi, Vivekananda, Liu, Duan, Ho, Ming-Fen, Grassi, Angela R, Wei, Lixuan, Moon, Irene, Vierkant, Robert A, Larson, Nicholas B, Lazaridis, Konstantinos N, Athreya, Arjun P, Wang, Liewei, Weinshilboum, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759330/
https://www.ncbi.nlm.nih.gov/pubmed/35861636
http://dx.doi.org/10.1093/hmg/ddac157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759330/
https://www.ncbi.nlm.nih.gov/pubmed/35861636
http://dx.doi.org/10.1093/hmg/ddac157

Ejemplares similares