Clock genes rescue nphp mutations in zebrafish

The zebrafish pronephros model, using morpholino oligonucleotides (MO) to deplete target genes, has been extensively used to characterize human ciliopathy phenotypes. Recently, discrepancies between MO and genetically defined mutants have questioned this approach. We analyzed zebrafish with mutation...

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Detalles Bibliográficos
Autores principales: Kayser, Nicolas, Zaiser, Friedemann, Veenstra, Anna C, Wang, Hui, Göcmen, Burulca, Eckert, Priska, Franz, Henriette, Köttgen, Anna, Walz, Gerd, Yakulov, Toma A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759334/
https://www.ncbi.nlm.nih.gov/pubmed/35861640
http://dx.doi.org/10.1093/hmg/ddac160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759334/
https://www.ncbi.nlm.nih.gov/pubmed/35861640
http://dx.doi.org/10.1093/hmg/ddac160

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