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Clock genes rescue nphp mutations in zebrafish
The zebrafish pronephros model, using morpholino oligonucleotides (MO) to deplete target genes, has been extensively used to characterize human ciliopathy phenotypes. Recently, discrepancies between MO and genetically defined mutants have questioned this approach. We analyzed zebrafish with mutation...
Autores principales: | Kayser, Nicolas, Zaiser, Friedemann, Veenstra, Anna C, Wang, Hui, Göcmen, Burulca, Eckert, Priska, Franz, Henriette, Köttgen, Anna, Walz, Gerd, Yakulov, Toma A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759334/ https://www.ncbi.nlm.nih.gov/pubmed/35861640 http://dx.doi.org/10.1093/hmg/ddac160 |
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