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Extracellular arginine is required but the arginine transporter CAT3 (Slc7a3) is dispensable for mouse normal and malignant hematopoiesis

Amino acid-mediated metabolism is one of the key catabolic and anabolic processes involved in diverse cellular functions. However, the role of the semi-essential amino acid arginine in normal and malignant hematopoietic cell development is poorly understood. Here we report that a continuous supply o...

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Detalles Bibliográficos
Autores principales: Yan, Yuhan, Chen, Chao, Li, Zhiguo, Zhang, Jing, Park, Narin, Qu, Cheng-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759514/
https://www.ncbi.nlm.nih.gov/pubmed/36528691
http://dx.doi.org/10.1038/s41598-022-24554-2