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Extracellular arginine is required but the arginine transporter CAT3 (Slc7a3) is dispensable for mouse normal and malignant hematopoiesis
Amino acid-mediated metabolism is one of the key catabolic and anabolic processes involved in diverse cellular functions. However, the role of the semi-essential amino acid arginine in normal and malignant hematopoietic cell development is poorly understood. Here we report that a continuous supply o...
Autores principales: | Yan, Yuhan, Chen, Chao, Li, Zhiguo, Zhang, Jing, Park, Narin, Qu, Cheng-Kui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759514/ https://www.ncbi.nlm.nih.gov/pubmed/36528691 http://dx.doi.org/10.1038/s41598-022-24554-2 |
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