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Stereodivergent synthesis of chiral succinimides via Rh-catalyzed asymmetric transfer hydrogenation

Chiral succinimide moieties are ubiquitous in biologically active natural products and pharmaceuticals. Until today, despite the great interest, little success has been made for stereodivergent synthesis of chiral succinimides. Here, we report a general and efficient method for accessing 3,4-disubst...

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Detalles Bibliográficos
Autores principales: Wang, Fangyuan, Zhang, Zongpeng, Chen, Yu, Ratovelomanana-Vidal, Virginie, Yu, Peiyuan, Chen, Gen-Qiang, Zhang, Xumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759521/
https://www.ncbi.nlm.nih.gov/pubmed/36528669
http://dx.doi.org/10.1038/s41467-022-35124-5