Direct imaging of intracellular RNA, DNA, and liquid–liquid phase separated membraneless organelles with Raman microspectroscopy

Methodologies for direct intracellular imaging of RNA and DNA are necessary for the advancement of bioimaging. Here we show direct label-free imaging of RNA and DNA in single cells by isolating their accurate Raman spectra. Raman images of DNA from interphase cells show intact nucleus, while those f...

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Detalles Bibliográficos
Autores principales: Samuel, Ashok Zachariah, Sugiyama, Kaori, Ando, Masahiro, Takeyama, Haruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759543/
https://www.ncbi.nlm.nih.gov/pubmed/36528668
http://dx.doi.org/10.1038/s42003-022-04342-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759543/
https://www.ncbi.nlm.nih.gov/pubmed/36528668
http://dx.doi.org/10.1038/s42003-022-04342-4

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