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Direct imaging of intracellular RNA, DNA, and liquid–liquid phase separated membraneless organelles with Raman microspectroscopy
Methodologies for direct intracellular imaging of RNA and DNA are necessary for the advancement of bioimaging. Here we show direct label-free imaging of RNA and DNA in single cells by isolating their accurate Raman spectra. Raman images of DNA from interphase cells show intact nucleus, while those f...
Autores principales: | Samuel, Ashok Zachariah, Sugiyama, Kaori, Ando, Masahiro, Takeyama, Haruko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759543/ https://www.ncbi.nlm.nih.gov/pubmed/36528668 http://dx.doi.org/10.1038/s42003-022-04342-4 |
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