Fetal pulmonary hypertension: dysregulated microRNA-34c-Notch1 axis contributes to impaired angiogenesis in an ovine model

BACKGROUND: Persistent pulmonary hypertension of the newborn (PPHN) occurs when pulmonary vascular resistance (PVR) fails to decrease at birth. Decreased angiogenesis in lung contributes to persistence of high PVR at birth. MicroRNAs (miRNAs) regulate gene expression through transcript binding and d...

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Detalles Bibliográficos
Autores principales: Mukherjee, Devashis, Rana, Ujala, Kriegel, Alison J., Liu, Pengyuan, Michalkiewicz, Teresa, Konduri, Girija Ganesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759620/
https://www.ncbi.nlm.nih.gov/pubmed/35717485
http://dx.doi.org/10.1038/s41390-022-02151-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759620/
https://www.ncbi.nlm.nih.gov/pubmed/35717485
http://dx.doi.org/10.1038/s41390-022-02151-3

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