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Fetal pulmonary hypertension: dysregulated microRNA-34c-Notch1 axis contributes to impaired angiogenesis in an ovine model
BACKGROUND: Persistent pulmonary hypertension of the newborn (PPHN) occurs when pulmonary vascular resistance (PVR) fails to decrease at birth. Decreased angiogenesis in lung contributes to persistence of high PVR at birth. MicroRNAs (miRNAs) regulate gene expression through transcript binding and d...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759620/ https://www.ncbi.nlm.nih.gov/pubmed/35717485 http://dx.doi.org/10.1038/s41390-022-02151-3 |