Cargando…

N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA

BACKGROUND: N‐acetyltransferase 10 (NAT10) is the only enzyme known to mediate the N4‐acetylcytidine (ac4C) modification of mRNA and is crucial for mRNA stability and translation efficiency. However, its role in cancer development and prognosis has not yet been explored. This study aimed to examine...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Xiao, Wang, Qi, Zhou, You, Zhang, Dachuan, Geng, Yiting, Hu, Wenwei, Wu, Changping, Shi, Yufang, Jiang, Jingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759759/
https://www.ncbi.nlm.nih.gov/pubmed/36209353
http://dx.doi.org/10.1002/cac2.12363