Cargando…
N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA
BACKGROUND: N‐acetyltransferase 10 (NAT10) is the only enzyme known to mediate the N4‐acetylcytidine (ac4C) modification of mRNA and is crucial for mRNA stability and translation efficiency. However, its role in cancer development and prognosis has not yet been explored. This study aimed to examine...
Autores principales: | Zheng, Xiao, Wang, Qi, Zhou, You, Zhang, Dachuan, Geng, Yiting, Hu, Wenwei, Wu, Changping, Shi, Yufang, Jiang, Jingting |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759759/ https://www.ncbi.nlm.nih.gov/pubmed/36209353 http://dx.doi.org/10.1002/cac2.12363 |
Ejemplares similares
-
Phase separation of FSP1 promotes ferroptosis
por: Nakamura, Toshitaka, et al.
Publicado: (2023) -
Structural insights into FSP1 catalysis and ferroptosis inhibition
por: Lv, Yun, et al.
Publicado: (2023) -
ACSL1-induced ferroptosis and platinum resistance in ovarian cancer by increasing FSP1 N-myristylation and stability
por: Zhang, Qingyu, et al.
Publicado: (2023) -
LINC01133 can induce acquired ferroptosis resistance by enhancing the FSP1 mRNA stability through forming the LINC01133-FUS-FSP1 complex
por: Wang, Shaowen, et al.
Publicado: (2023) -
Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation
por: Nakamura, Toshitaka, et al.
Publicado: (2023)