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Effects of Shenling Baizhu powder on pyrotinib-induced diarrhea: analysis of gut microbiota, metabonomics, and network pharmacology

BACKGROUND: Shenling Baizhu Powder (SBP) is a traditional Chinese medicine (TCM) prescription, which has the good efficacy on gastrointestinal toxicity. In this study, we used gut microbiota analysis, metabonomics and network pharmacology to investigate the therapeutic effect of SBP on pyrotinib-ind...

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Detalles Bibliográficos
Autores principales: Lai, Jingjiang, Jiang, Fengxian, Zhuo, Xiaoli, Xu, Xiaoying, Liu, Lei, Yin, Ke, Wang, Jingliang, Zhao, Jing, Xu, Wei, Liu, Hongjing, Wang, Xuan, Jiang, Wen, Wang, Ke, Yang, Shuping, Guo, Honglin, Qi, Fanghua, Yuan, Xiaotian, Lin, Xiaoyan, Fu, Guobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759852/
https://www.ncbi.nlm.nih.gov/pubmed/36528679
http://dx.doi.org/10.1186/s13020-022-00696-3