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Berberine increases stromal production of Wnt molecules and activates Lgr5(+) stem cells to promote epithelial restitution in experimental colitis

BACKGROUND: Inflammatory bowel diseases (IBDs) are characterized by sustained inflammation and/or ulcers along the lower digestive tract, and have complications such as colorectal cancer and inflammation in other organs. The current treatments for IBDs, which affect 0.3% of the global population, ma...

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Detalles Bibliográficos
Autores principales: Luo, Zecheng, Li, Zihao, Liang, Zheng, Wang, Lin, He, Guanlin, Wang, Dongdi, Shen, Lei, Wang, Zhengting, Ma, Xiuying, Geng, Funeng, Wang, Haozhong, Liu, Wenping, Liu, Huijuan, Li, Baojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759859/
https://www.ncbi.nlm.nih.gov/pubmed/36528592
http://dx.doi.org/10.1186/s12915-022-01492-z