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A purified and lyophilized Pseudomonas aeruginosa derived pyocyanin induces promising apoptotic and necrotic activities against MCF-7 human breast adenocarcinoma

BACKGROUND: Pyocyanin, a specific extracellular secondary metabolite pigment produced by Pseudomonas aeruginosa, exhibits redox activity and has toxic effects on mammalian cells, making it a new and potent alternative for treating cancer. Breast cancer (BC) treatment is now defied by acquired and de...

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Detalles Bibliográficos
Autores principales: Abdelaziz, Ahmed A., Kamer, Amal M. Abo, Al-Monofy, Khaled B., Al-Madboly, Lamiaa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759863/
https://www.ncbi.nlm.nih.gov/pubmed/36528623
http://dx.doi.org/10.1186/s12934-022-01988-x