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Elevated Levels of PGE2-Metabolite in Cerebrospinal Fluid and Cox-2 Gene Polymorphisms in Patients with Chronic, Post Cholecystectomy Pain and Visceral Hyperalgesia Compared to Healthy Controls. A Hypothesis-Generating Pilot Study

PURPOSE: Chronic, abdominal pain remains a problem in a subset of patients after cholecystectomy. The cause is often obscure but central sensitization may be an important component and could theoretically be mediated by spinal PGE2, which is regulated by several cytokines. The aim of the study was t...

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Detalles Bibliográficos
Autores principales: Blichfeldt-Eckhardt, Morten Rune, Olsen, Dorte Aalund, Andersen, Rikke Fredslund, Toft, Palle, Bendix, Laila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760037/
https://www.ncbi.nlm.nih.gov/pubmed/36540575
http://dx.doi.org/10.2147/JPR.S387502