Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma

Salivary adenoid cystic carcinoma (ACC) is a rare, biologically unique biphasic tumor that consists of malignant myoepithelial and luminal cells. MYB and Notch signaling have been implicated in ACC pathophysiology, but in vivo descriptions of these two programs in human tumors and investigation into...

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Detalles Bibliográficos
Autores principales: Parikh, Anuraag S., Wizel, Avishai, Davis, Daniel, Lefranc-Torres, Armida, Rodarte-Rascon, Alejandro I., Miller, Lauren E., Emerick, Kevin S., Varvares, Mark A., Deschler, Daniel G., Faquin, William C., Aster, Jon C., Lin, Derrick T., Bernstein, Bradley E., Drier, Yotam, Puram, Sidharth V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760094/
https://www.ncbi.nlm.nih.gov/pubmed/36450256
http://dx.doi.org/10.1016/j.celrep.2022.111743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760094/
https://www.ncbi.nlm.nih.gov/pubmed/36450256
http://dx.doi.org/10.1016/j.celrep.2022.111743

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