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High doses of zoledronic acid induce differential effects on femur and jawbone microstructure

OBJECTIVES: The aim of this study is to investigate the long‐term effects on jaw and femur bone induced by oncologic doses of zoledronic acid in a young rat model. MATERIAL AND METHODS: Six 12‐week‐old male Wistar rats received zoledronic acid (0.6 mg/kg) and six control rats received saline solutio...

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Detalles Bibliográficos
Autores principales: Soares, Mariana Q. S., Van Dessel, Jeroen, Jacobs, Reinhilde, Ferreira, Gustavo Z., da Silva Santos, Paulo Sérgio, Nicolielo, Laura F. P., Duarte, Marco A. H., Rubira‐Bullen, Izabel R. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760133/
https://www.ncbi.nlm.nih.gov/pubmed/35933703
http://dx.doi.org/10.1002/cre2.643