Development and In vivo Pharmacokinetic and Pharmacodynamic Evaluation of an Oral Innovative Cyclodextrin Complexed Lipid Nanoparticles of Irbesartan Formulation for Enhanced Bioavailability

Background: Irbesartan (IR) is used in the treatment of hypertension, heart failure, and nephropathy in Type II diabetes. IR bioavailability is limited by poor solubility and presystemic metabolism. In our previous investigations, cyclodextrin (HPβCD) complexed solid lipid nanoparticles (SLNs) of IR...

Descripción completa

Detalles Bibliográficos
Autores principales: Dudhipala, Narendar, Ettireddy, Swetha, Youssef, Ahmed Adel Ali, Puchchakayala, Goverdhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760361/
https://www.ncbi.nlm.nih.gov/pubmed/36593793
http://dx.doi.org/10.7150/ntno.78102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760361/
https://www.ncbi.nlm.nih.gov/pubmed/36593793
http://dx.doi.org/10.7150/ntno.78102

Ejemplares similares