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Crossroads between copper ions and amyloid formation in Parkinson’s disease

Copper (Cu) ion dys-homeostasis and α-synclein amyloid deposits are two hallmarks of Parkinson’s disease (PD). Here, I will discuss the connections between these features, with a major focus on the role of Cu in the α-synuclein (aS) amyloid formation process. The structurally disordered aS monomer c...

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Detalles Bibliográficos
Autor principal: Wittung-Stafshede, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760422/
https://www.ncbi.nlm.nih.gov/pubmed/35757906
http://dx.doi.org/10.1042/EBC20220043