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How phosphorylation impacts intrinsically disordered proteins and their function

Phosphorylation is the most common post-translational modification (PTM) in eukaryotes, occurring particularly frequently in intrinsically disordered proteins (IDPs). These proteins are highly flexible and dynamic by nature. Thus, it is intriguing that the addition of a single phosphoryl group to a...

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Detalles Bibliográficos
Autores principales: Newcombe, Estella A., Delaforge, Elise, Hartmann-Petersen, Rasmus, Skriver, Karen, Kragelund, Birthe B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760426/
https://www.ncbi.nlm.nih.gov/pubmed/36350035
http://dx.doi.org/10.1042/EBC20220060