The developmental regulator HAND1 inhibits gastric carcinogenesis through enhancing ER stress apoptosis via targeting CHOP and BAK which is augmented by cisplatin

Epigenetic disruption of tumor suppressor genes, particularly aberrant CpG methylation, plays a crucial role in gastric cancer (GC) pathogenesis. Through CpG methylome and expression profiling, a developmental transcription factor - Hand-And-Neural-crest-Derivative-expressed 1 (HAND1), was identifie...

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Detalles Bibliográficos
Autores principales: Kuang, Yeye, He, Zhanglian, Li, Lili, Wang, Chan, Cheng, Xiaoqing, Shi, Qinglan, Fu, Guoxiang, Ying, Jianming, Tao, Qian, Hu, Xiaotong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760445/
https://www.ncbi.nlm.nih.gov/pubmed/36594085
http://dx.doi.org/10.7150/ijbs.76345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760445/
https://www.ncbi.nlm.nih.gov/pubmed/36594085
http://dx.doi.org/10.7150/ijbs.76345

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