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Multi-omics insights into the biological mechanisms underlying statistical gene-by-lifestyle interactions with smoking and alcohol consumption

Though both genetic and lifestyle factors are known to influence cardiometabolic outcomes, less attention has been given to whether lifestyle exposures can alter the association between a genetic variant and these outcomes. The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Co...

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Detalles Bibliográficos
Autores principales: Majarian, Timothy D., Bentley, Amy R., Laville, Vincent, Brown, Michael R., Chasman, Daniel I., de Vries, Paul S., Feitosa, Mary F., Franceschini, Nora, Gauderman, W. James, Marchek, Casey, Levy, Daniel, Morrison, Alanna C., Province, Michael, Rao, Dabeeru C., Schwander, Karen, Sung, Yun Ju, Rotimi, Charles N., Aschard, Hugues, Gu, C. Charles, Manning, Alisa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760722/
https://www.ncbi.nlm.nih.gov/pubmed/36544485
http://dx.doi.org/10.3389/fgene.2022.954713