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Pathological complete response after neoadjuvant immunotherapy combined with chemotherapy in pediatric rectal carcinoma: A case report

BACKGROUND: Pediatric colorectal carcinoma (PCRC) is a rare non-embryonal tumor with an incidence of 0.1% to 1% of adults. Immune checkpoint inhibitors (ICIs) targeting programmed death-1 (PD-1) have shown significant efficacy in defective mismatch repair/Microsatellite instability-high (dMMR/MSI-H)...

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Detalles Bibliográficos
Autores principales: Cao, Xiaomeng, Luo, Jianwei, Zhao, Baoyin, Fu, Hongjiang, Kang, Wendi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760745/
https://www.ncbi.nlm.nih.gov/pubmed/36544760
http://dx.doi.org/10.3389/fimmu.2022.1036181