Optimization of the extraction process and metabonomics analysis of uric acid-reducing active substances from Gymnadenia R.Br. and its protective effect on hyperuricemia zebrafish

BACKGROUND: As Gymnadenia R.Br. (Gym) has an obvious uric acid-lowering effect, but its specific bioactive substances and mechanism are still unclear. The key metabolites and pathways used by Gym to reduce uric acid (UA) were identify. METHODS: An optimized extraction process for urate-lowering acti...

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Detalles Bibliográficos
Autores principales: Chen, Tianrong, Pubu, Duoji, Zhang, Wenhui, Meng, Shengya, Yu, Cuicui, Yin, Xiaoqing, Liu, Jiale, Zhang, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760756/
https://www.ncbi.nlm.nih.gov/pubmed/36545468
http://dx.doi.org/10.3389/fnut.2022.1054294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760756/
https://www.ncbi.nlm.nih.gov/pubmed/36545468
http://dx.doi.org/10.3389/fnut.2022.1054294

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