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Downregulation of T-cell cytotoxic marker IL18R1 promotes cancer proliferation and migration and is associated with dismal prognosis and immunity in lung squamous cell carcinoma

Immunotherapy can improve the survival of patients with advanced lung squamous cell carcinoma (LUSC). T cytotoxic cells are one of the main members of the immune microenvironment. Herein, we aimed to identify the roles of T-cell cytotoxic markers interleukin 18 (IL18) receptor 1 (IL18R1) in the LUSC...

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Detalles Bibliográficos
Autores principales: Guo, Qiang, Wu, Chuang-Yan, Jiang, Ni, Tong, Song, Wan, Jun-Hao, Xiao, Xiao-Yue, Mei, Pei-Yuan, Liu, Hua-Song, Wang, Si-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760870/
https://www.ncbi.nlm.nih.gov/pubmed/36544782
http://dx.doi.org/10.3389/fimmu.2022.986447